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Hyaluronic acid dermal fillers



Since 2008, the use of Hyaluronic dermal fillers has been on the rise as one of the most popular non-permanent injectable substances to treat skin wrinkles and furrows that characterize aging skin. Statistics from ASAPS or the American Society for Aesthetic Plastic Surgery reveal that Hyaluronic dermal fillers have overtaken collagen injections for 3rd place among cosmetic aesthetic procedures with 1.26 million treatments in the US.

In the UK, the acid based Hyaluronic dermal fillers comprise the leading injectable solutions for reversing the signs of aging with popular brands like Restylane®, Perlane®, Juvederm® and Hylaform®.

Hyaluronic Dermal Fillers Defined

Hyaluronic acid is a naturally produced carbohydrate or polysaccharide occurring in spaces between cells in connective tissues in animals and people. Before being discovered as an excellent non-allergenic dermal filler, it has been earlier used to treat arthritic joints with injections of the substance in aiding movement. Hyaluronic dermal fillers have become popular most likely because of the substance's better bio-compatibility with human bodies resulting in significantly less allergic reactions and thus, require no prior testing.

Notable Hyaluronic Cosmetic Brands

Hyaluronic dermal fillers are commonly used to treat facial wrinkles, forehead frown lines, smile lines or nasolabial folds, crow's feet and also used for lip augmentation. They offer a longer lasting cosmetic effect than collagen-based dermal fillers with none of the side-effects, hence, its popularity, notwithstanding a slightly more expensive price tag per syringe.

Across all the brands, the average cost is around £300 per syringe, about a hundred bucks more than using collagen, but this is expected to even-out soon. And like any injectable cosmetic procedure, topical anesthesia on the skin area to be treated is required. As a non-permanent treatment, regular injections are needed usually at 3-9 month intervals depending on the extent of treatment.
  • Juvederm Ultra is one of the latest Hyaluronic dermal fillers to get FDA certification in June of 2006 and is used to treat mild to moderate cases of skin wrinkles, particularly creases around the lips.
  • Restylane was first introduced in 1996 and is one of the earliest hyaluronic dermal filler to get FDA approval in December 2003. It is best used for mild or fine skin creases and is the preferred solution for pumping eyebrows and smoothing lines under the eyes and around lips. It is also used in enhancing or giving better definition to cheeks and jawlines as well as softening the looks of scarred skin and boney hands.
  • Hylaform and Captique were FDA-approved in 2004 and are the preferred hyaluronic dermal fillers for treating moderate to severe skin wrinkles and creases around the nose and lips notably smile lines or nasolabial grooves. The hyaluronic acid in Hylaform is extracted from rooster combs while that in Captique is derived from non-animal sources.
  • Perlane got its FDA approval in March of 2007 and has a thicker consistency than Restylane. Both are crystal clear injectable gels that are the most popular among Hyaluronic dermal fillers.
  • There are new Hyaluronic dermal fillers that have anesthetic chemicals like lidocaine mixed that can render the use of topical anesthetics unnecessary. Prevelle Silk™ got is FDA nod in March 2008 and is effective for treating moderate to severe wrinkles and skin grooves like nasolabial folds. Puragee® still has a pending FDA approval.



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Hyaluronic acid Dermal Filler






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